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Manipulation of Salmonella Typhi Gene Expression Impacts Innate Cell Responses in the Human Intestinal Mucosa

Although immunity induced by typhoid fever is moderated and short-lived, typhoid vaccination with the attenuated Ty21a oral vaccine generates long-lasting protection rates reaching up to 92%. Thus, there are important differences on how wild-type Salmonella and typhoid vaccine strains stimulate host...

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Detalles Bibliográficos
Autores principales: Salerno-Gonçalves, Rosângela, Galen, James E., Levine, Myron M., Fasano, Alessio, Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221971/
https://www.ncbi.nlm.nih.gov/pubmed/30443257
http://dx.doi.org/10.3389/fimmu.2018.02543