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Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in Patients With Chronic Hepatitis C Virus Genotype 1 Infection Receiving Opioid Substitution Therapy: A Post Hoc Analysis of 12 Clinical Trials

BACKGROUND: We evaluated the impact of opioid substitution therapy (OST) on the completion, adherence, efficacy, and safety of the 3-direct-acting antiviral regimen of ombitasvir, paritaprevir (identified by AbbVie and Enanta) co-dosed with ritonavir, and dasabuvir ± ribavirin among patients infecte...

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Detalles Bibliográficos
Autores principales: Grebely, Jason, Puoti, Massimo, Wedemeyer, Heiner, Cooper, Curtis, Sulkowski, Mark S, Foster, Graham R, Berg, Thomas, Villa, Erica, Rodriguez-Perez, Federico, Wyles, David L, Schnell, Gretja, Alami, Negar N, Zhang, Zhenzhen, Dumas, Emily, Dore, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222025/
https://www.ncbi.nlm.nih.gov/pubmed/30430131
http://dx.doi.org/10.1093/ofid/ofy248