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Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in Patients With Chronic Hepatitis C Virus Genotype 1 Infection Receiving Opioid Substitution Therapy: A Post Hoc Analysis of 12 Clinical Trials
BACKGROUND: We evaluated the impact of opioid substitution therapy (OST) on the completion, adherence, efficacy, and safety of the 3-direct-acting antiviral regimen of ombitasvir, paritaprevir (identified by AbbVie and Enanta) co-dosed with ritonavir, and dasabuvir ± ribavirin among patients infecte...
Autores principales: | Grebely, Jason, Puoti, Massimo, Wedemeyer, Heiner, Cooper, Curtis, Sulkowski, Mark S, Foster, Graham R, Berg, Thomas, Villa, Erica, Rodriguez-Perez, Federico, Wyles, David L, Schnell, Gretja, Alami, Negar N, Zhang, Zhenzhen, Dumas, Emily, Dore, Gregory J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222025/ https://www.ncbi.nlm.nih.gov/pubmed/30430131 http://dx.doi.org/10.1093/ofid/ofy248 |
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