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Complement Susceptibility in Relation to Genome Sequence of Recent Klebsiella pneumoniae Isolates from Thai Hospitals

The capacity to resist the bactericidal action of complement (C′) is a strong but poorly understood virulence trait in Klebsiella spp. Killing requires activation of one or more C′ pathways, assembly of C5b-9 membrane attack complexes (MACs) on the surface of the outer membrane (OM), and penetration...

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Detalles Bibliográficos
Autores principales: Loraine, Jessica, Heinz, Eva, De Sousa Almeida, Jessica, Milevskyy, Oleksandr, Voravuthikunchai, Supayang P., Srimanote, Potjanee, Kiratisin, Pattarachai, Thomson, Nicholas R., Taylor, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222052/
https://www.ncbi.nlm.nih.gov/pubmed/30404929
http://dx.doi.org/10.1128/mSphere.00537-18