Cargando…

Identification of an Exceptionally Long Intron in the HAC1 Gene of Candida parapsilosis

The unfolded protein response (UPR) in the endoplasmic reticulum (ER) is well conserved in eukaryotes from metazoa to yeast. The transcription factor HAC1 is a major regulator of the UPR in many eukaryotes. Deleting HAC1 in the yeast Candida parapsilosis rendered cells more sensitive to DTT, a known...

Descripción completa

Detalles Bibliográficos
Autores principales: Iracane, Elise, Donovan, Paul D., Ola, Mihaela, Butler, Geraldine, Holland, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222058/
https://www.ncbi.nlm.nih.gov/pubmed/30404939
http://dx.doi.org/10.1128/mSphere.00532-18