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Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma()()

Hepatoblastoma is the most common primary liver tumor in children, but treatment has not changed significantly in the past 20 years. We have previously demonstrated that Proviral Integration site for Moloney murine leukemia (PIM) kinases promote tumorigenesis in hepatoblastoma. Stem cell-like cancer...

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Detalles Bibliográficos
Autores principales: Stafman, Laura L., Williams, Adele P., Garner, Evan F., Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Whelan, Kimberly, Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222086/
https://www.ncbi.nlm.nih.gov/pubmed/30412911
http://dx.doi.org/10.1016/j.tranon.2018.10.008