Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family

Flavin-dependent enzymes catalyze many oxidations, including formation of ring structures in natural products. The gene cluster for biosynthesis of fumisoquins, secondary metabolites structurally related to isoquinolines, in the filamentous fungus Aspergillus fumigatus harbors a gene that encodes a...

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Detalles Bibliográficos
Autores principales: Lahham, Majd, Pavkov-Keller, Tea, Fuchs, Michael, Niederhauser, Johannes, Chalhoub, Gabriel, Daniel, Bastian, Kroutil, Wolfgang, Gruber, Karl, Macheroux, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222107/
https://www.ncbi.nlm.nih.gov/pubmed/30194285
http://dx.doi.org/10.1074/jbc.RA118.004227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222107/
https://www.ncbi.nlm.nih.gov/pubmed/30194285
http://dx.doi.org/10.1074/jbc.RA118.004227

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