The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

Zika virus (ZIKV) infection of neural progenitor cells (NPCs) in utero is associated with neurological disorders, such as microcephaly, but a detailed molecular understanding of ZIKV-induced pathogenesis is lacking. Here we show that in vitro ZIKV infection of human cells, including NPCs, causes dis...

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Detalles Bibliográficos
Autores principales: Fontaine, Krystal A., Leon, Kristoffer E., Khalid, Mir M., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia A., Shah, Priya S., Finkbeiner, Steve, Krogan, Nevan J., Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222128/
https://www.ncbi.nlm.nih.gov/pubmed/30401782
http://dx.doi.org/10.1128/mBio.02126-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222128/
https://www.ncbi.nlm.nih.gov/pubmed/30401782
http://dx.doi.org/10.1128/mBio.02126-18

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