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The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein
Zika virus (ZIKV) infection of neural progenitor cells (NPCs) in utero is associated with neurological disorders, such as microcephaly, but a detailed molecular understanding of ZIKV-induced pathogenesis is lacking. Here we show that in vitro ZIKV infection of human cells, including NPCs, causes dis...
Autores principales: | Fontaine, Krystal A., Leon, Kristoffer E., Khalid, Mir M., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia A., Shah, Priya S., Finkbeiner, Steve, Krogan, Nevan J., Ott, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222128/ https://www.ncbi.nlm.nih.gov/pubmed/30401782 http://dx.doi.org/10.1128/mBio.02126-18 |
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