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Unexpected Evolution of Lesion-Recognition Modules in Eukaryotic NER and Kinetoplast DNA Dynamics Proteins from Bacterial Mobile Elements

The provenance of several components of major uniquely eukaryotic molecular machines are increasingly being traced back to prokaryotic biological conflict systems. Here, we demonstrate that the N-terminal single-stranded DNA-binding domain from the anti-restriction protein ArdC, deployed by bacteria...

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Detalles Bibliográficos
Autores principales: Krishnan, Arunkumar, Burroughs, A. Maxwell, Iyer, Lakshminarayan M., Aravind, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222260/
https://www.ncbi.nlm.nih.gov/pubmed/30396152
http://dx.doi.org/10.1016/j.isci.2018.10.017