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Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase

AIDS caused by the infection of HIV is a prevalent problem today. Rapid development of drug resistance to existing drug classes has called for the discovery of new targets. Within the three major enzymes (i.e., HIV-1 protease, HIV-1 reverse transcriptase and HIV-1 integrase [IN]) of the viral replic...

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Detalles Bibliográficos
Autores principales: Choi, Eungi, Mallareddy, Jayapal Reddy, Lu, Dai, Kolluru, Srikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222271/
https://www.ncbi.nlm.nih.gov/pubmed/30416746
http://dx.doi.org/10.4155/fsoa-2018-0060