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In Vitro and In Silico Insights into sEH Inhibitors with Amide-Scaffold from the Leaves of Capsicum chinense Jacq.

Two compounds termed 1 and 2 were isolated from the leaves of Capsicum chinense using column chromatography. Their structures were identified as amide scaffolds by analyzing spectroscopic signals. Compounds 1 and 2 have been confirmed to be competitive soluble epoxide hydrolase (sEH) inhibitors that...

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Detalles Bibliográficos
Autores principales: Kim, Jang Hoon, Jo, Yeong Deuk, Kim, Hyo-Young, Kim, Bo-Ram, Nam, Bomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222292/
https://www.ncbi.nlm.nih.gov/pubmed/30425801
http://dx.doi.org/10.1016/j.csbj.2018.10.017