Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery

Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1–G4), modified to bear 6–48 amino en...

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Detalles Bibliográficos
Autores principales: Stenström, Patrik, Manzanares, Dario, Zhang, Yuning, Ceña, Valentin, Malkoch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222295/
https://www.ncbi.nlm.nih.gov/pubmed/30110914
http://dx.doi.org/10.3390/molecules23082028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222295/
https://www.ncbi.nlm.nih.gov/pubmed/30110914
http://dx.doi.org/10.3390/molecules23082028

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