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A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

There is growing recognition regarding the role of intracellular amyloid beta (Aβ) in the Alzheimer’s disease process, which has been linked with aberrant signaling and the disruption of protein degradation mechanisms. Most notably, intraneuronal Aβ likely underlies the oxidative stress and mitochon...

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Detalles Bibliográficos
Autores principales: Hilt, Silvia, Altman, Robin, Kálai, Tamás, Maezawa, Izumi, Gong, Qizhi, Wachsmann-Hogiu, Sebastian, Jin, Lee-Way, Voss, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222334/
https://www.ncbi.nlm.nih.gov/pubmed/30103547
http://dx.doi.org/10.3390/molecules23082010