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Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25

Eukaryotic transcription initiation is mediated by interactions between transcriptional activators and the mediator coactivator complex. Molecular interaction of p53 transcription factor with mediator complex subunit 25 (MED25) is essential for its target gene transcription. In this study, we charac...

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Detalles Bibliográficos
Autores principales: Lee, Min-Sung, Lim, Kyungeun, Lee, Mi-Kyung, Chi, Seung-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222444/
https://www.ncbi.nlm.nih.gov/pubmed/30360415
http://dx.doi.org/10.3390/molecules23102726