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Enantioseparation, Stereochemical Assignment and Chiral Recognition Mechanism of Sulfoxide-Containing Drugs

The distinct pharmacodynamic and pharmacokinetic properties of enantiopure sulfoxide drugs have stimulated us to systematically investigate their chiral separation, stereochemical assignment, and chiral recognition mechanism. Herein, four clinically widely-used sulfoxide drugs were chosen and optica...

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Detalles Bibliográficos
Autores principales: Xiong, Fei, Yang, Bei-Bei, Zhang, Jie, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222453/
https://www.ncbi.nlm.nih.gov/pubmed/30340337
http://dx.doi.org/10.3390/molecules23102680