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Ruthenium-Based Catalytic Systems Incorporating a Labile Cyclooctadiene Ligand with N-Heterocyclic Carbene Precursors for the Atom-Economic Alcohol Amidation Using Amines

Transition-metal-catalyzed amide-bond formation from alcohols and amines is an atom-economic and eco-friendly route. Herein, we identified a highly active in situ N-heterocyclic carbene (NHC)/ruthenium (Ru) catalytic system for this amide synthesis. Various substrates, including sterically hindered...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Miao, Yang, De Winter, Kimmy, Wang, Hua-Jing, Demeyere, Patrick, Yuan, Ye, Verpoort, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222456/
https://www.ncbi.nlm.nih.gov/pubmed/30241354
http://dx.doi.org/10.3390/molecules23102413