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New 2-Oxoindolin Phosphonates as Novel Agents to Treat Cancer: A Green Synthesis and Molecular Modeling

The work reports the facile synthesis of novel α-aminophosphonate derivatives coupled with indole-2,3-dione moieties, namely the diethyl(substituted phenyl/heteroaryl)(2-(2-oxoindolin-3-ylidene)hydrazinyl)methylphosphonates derivatives 4(a–n). One-pot three component Kabachnik-Fields reactions were...

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Detalles Bibliográficos
Autores principales: Tiwari, Shailee V., Sharif, Nawaz S., Gajare, Rekha I., Vazquez, Julio A. Seijas, Sangshetti, Jaiprakash N., Damale, Manoj D., Nikalje, Anna Pratima G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222476/
https://www.ncbi.nlm.nih.gov/pubmed/30096835
http://dx.doi.org/10.3390/molecules23081981