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Ganoderma tsugae Inhibits the SREBP-1/AR Axis Leading to Suppression of Cell Growth and Activation of Apoptosis in Prostate Cancer Cells

Recent research suggests that the activation of lipid biosynthesis (lipogenesis) is linked with prostate cancer (PCa) malignancy. Sterol regulatory element-binding protein-1 (SREBP-1) is a key transcriptional regulator controlling lipogenesis. Moreover, androgen receptor (AR) has been well defined t...

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Detalles Bibliográficos
Autores principales: Huang, Shih-Yin, Huang, Guan-Jhong, Wu, Hsi-Chin, Kao, Ming-Ching, Huang, Wen-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222511/
https://www.ncbi.nlm.nih.gov/pubmed/30301150
http://dx.doi.org/10.3390/molecules23102539