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Comparative Study of Carborane- and Phenyl-Modified Adenosine Derivatives as Ligands for the A2A and A3 Adenosine Receptors Based on a Rigid in Silico Docking and Radioligand Replacement Assay

Adenosine receptors are involved in many physiological processes and pathological conditions and are therefore attractive therapeutic targets. To identify new types of effective ligands for these receptors, a library of adenosine derivatives bearing a boron cluster or phenyl group in the same positi...

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Detalles Bibliográficos
Autores principales: Vincenzi, Marian, Bednarska, Katarzyna, Leśnikowski, Zbigniew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222516/
https://www.ncbi.nlm.nih.gov/pubmed/30044380
http://dx.doi.org/10.3390/molecules23081846