Permeability of Ciprofloxacin-Loaded Polymeric Micelles Including Ginsenoside as P-glycoprotein Inhibitor through a Caco-2 Cells Monolayer as an Intestinal Absorption Model

The low oral bioavailability of ciprofloxacin is associated with two distinct challenges: its low aqueous solubility and efflux by p-glycoproteins (P-gp) in the intestinal membrane. Several studies were conducted in order to improve its solubility and permeability through the gastrointestinal membra...

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Detalles Bibliográficos
Autores principales: Sharif Makhmal Zadeh, Behzad, Esfahani, Golbarg, Salimi, Anayatollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222528/
https://www.ncbi.nlm.nih.gov/pubmed/30065147
http://dx.doi.org/10.3390/molecules23081904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222528/
https://www.ncbi.nlm.nih.gov/pubmed/30065147
http://dx.doi.org/10.3390/molecules23081904

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