Turning Stem Cells Bad: Generation of Clinically Relevant Models of Human Acute Myeloid Leukemia through Gene Delivery- or Genome Editing-Based Approaches

Acute myeloid leukemia (AML), the most common acute leukemia in the adult, is believed to arise as a consequence of multiple molecular events that confer on primitive hematopoietic progenitors unlimited self-renewal potential and cause defective differentiation. A number of genetic aberrations, amon...

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Detalles Bibliográficos
Autores principales: Mesuraca, Maria, Amodio, Nicola, Chiarella, Emanuela, Scicchitano, Stefania, Aloisio, Annamaria, Codispoti, Bruna, Lucchino, Valeria, Montalcini, Ylenia, Bond, Heather M., Morrone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222541/
https://www.ncbi.nlm.nih.gov/pubmed/30126100
http://dx.doi.org/10.3390/molecules23082060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222541/
https://www.ncbi.nlm.nih.gov/pubmed/30126100
http://dx.doi.org/10.3390/molecules23082060

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