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Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans
We describe a simple bioinformatics method for biomarker discovery that is based on the analysis of global transcript levels in a population of inbred mouse strains showing variation for disease-related traits. This method has advantages such as controlled environment and accessibility to heart and...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222577/ https://www.ncbi.nlm.nih.gov/pubmed/30201759 http://dx.doi.org/10.1534/g3.118.200655 |