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Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans

We describe a simple bioinformatics method for biomarker discovery that is based on the analysis of global transcript levels in a population of inbred mouse strains showing variation for disease-related traits. This method has advantages such as controlled environment and accessibility to heart and...

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Detalles Bibliográficos
Autores principales:	Lin, Liang-Yu, Chun Chang, Sunny, O’Hearn, Jim, Hui, Simon T., Seldin, Marcus, Gupta, Pritha, Bondar, Galyna, Deng, Mario, Jauhiainen, Raimo, Kuusisto, Johanna, Laakso, Markku, Sinsheimer, Janet S., Deb, Arjun, Rau, Christoph, Ren, Shuxun, Wang, Yibin, Lusis, Aldons J., Wang, Jessica J., Huertas-Vazquez, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222577/ https://www.ncbi.nlm.nih.gov/pubmed/30201759 http://dx.doi.org/10.1534/g3.118.200655

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