Application of Neurokinin-1 Receptor in Targeted Strategies for Glioma Treatment. Part I: Synthesis and Evaluation of Substance P Fragments Labeled with (99m)Tc and (177)Lu as Potential Receptor Radiopharmaceuticals

Gliomas, particularly WHO grade IV glioblastoma multiforme, are one of the most common and aggressive primary tumors of the central nervous system. The neuropeptide, substance P (SP), is the physiological ligand of the neurokinin-1 (NK-1) receptor that is consistently overexpressed in glioblastoma c...

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Detalles Bibliográficos
Autores principales: Majkowska-Pilip, Agnieszka, Koźmiński, Przemysław, Wawrzynowska, Anna, Budlewski, Tadeusz, Kostkiewicz, Bogusław, Gniazdowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222600/
https://www.ncbi.nlm.nih.gov/pubmed/30301182
http://dx.doi.org/10.3390/molecules23102542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222600/
https://www.ncbi.nlm.nih.gov/pubmed/30301182
http://dx.doi.org/10.3390/molecules23102542

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