Determination of Novel Highly Effective Necrostatin Nec-1s in Rat Plasma by High Performance Liquid Chromatography Hyphenated with Quadrupole-Time-of-Flight Mass Spectrometry

Necrostatins have been shown to retard necroptosis, a programmed necrotic-like cell death, which has been shown to underlie pathophysiology of various diseases. Nec-1s, a novel highly effective necrostatin, overcomes some drawbacks of former necrostatin analogues. The determination of Nec-1s in biol...

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Detalles Bibliográficos
Autores principales: Mikuš, Peter, Pecher, Daniel, Rauová, Drahomíra, Horváth, Csaba, Szobi, Adrián, Adameová, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222636/
https://www.ncbi.nlm.nih.gov/pubmed/30081531
http://dx.doi.org/10.3390/molecules23081946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222636/
https://www.ncbi.nlm.nih.gov/pubmed/30081531
http://dx.doi.org/10.3390/molecules23081946

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