Selective Synthesis of 3-O-Palmitoyl-Silybin, a New-to-Nature Flavonolignan with Increased Protective Action against Oxidative Damages in Lipophilic Media

A selective acylation protocol using cerium chloride (CeCl(3)) as catalyst was applied to functionalize silybinin (1), a natural antioxidant flavonolignan from milk thistle fruit, in order to increase its solubility in lipophilic media while retaining its strong antioxidant activity. The selective e...

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Detalles Bibliográficos
Autores principales: Drouet, Samantha, Doussot, Joël, Garros, Laurine, Mathiron, David, Bassard, Solène, Favre-Réguillon, Alain, Molinié, Roland, Lainé, Éric, Hano, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222644/
https://www.ncbi.nlm.nih.gov/pubmed/30309022
http://dx.doi.org/10.3390/molecules23102594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222644/
https://www.ncbi.nlm.nih.gov/pubmed/30309022
http://dx.doi.org/10.3390/molecules23102594

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