HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence

HIV-1 integrase (IN) inhibitors represent a new class of highly effective anti-AIDS therapeutics. Current FDA-approved IN strand transfer inhibitors (INSTIs) share a common mechanism of action that involves chelation of catalytic divalent metal ions. However, the emergence of IN mutants having reduc...

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Detalles Bibliográficos
Autores principales: Zhao, Xue Zhi, Métifiot, Mathieu, Kiselev, Evgeny, Kessl, Jacques J., Maddali, Kasthuraiah, Marchand, Christophe, Kvaratskhelia, Mamuka, Pommier, Yves, Burke, Terrence R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222646/
https://www.ncbi.nlm.nih.gov/pubmed/30049955
http://dx.doi.org/10.3390/molecules23081858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222646/
https://www.ncbi.nlm.nih.gov/pubmed/30049955
http://dx.doi.org/10.3390/molecules23081858

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