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The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs

The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0.1–1.0%) on the pulmonary absorption of macromolecule...

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Detalles Bibliográficos
Autores principales: Lu, Juan, Li, Nannan, Gao, Yaochun, Li, Nan, Guo, Yifei, Liu, Haitao, Chen, Xi, Zhu, Chunyan, Dong, Zhengqi, Yamamoto, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222674/
https://www.ncbi.nlm.nih.gov/pubmed/30103462
http://dx.doi.org/10.3390/molecules23082001