Cargando…
Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity
1,3-Dipolar cycloaddition of N-methyl C-(diethoxyphosphoryl) nitrone to N3-substituted 6-bromo-2-vinyl-3H-quinazolin-4-ones gave (3-diethoxyphosphoryl) isoxazolidines substituted at C5 with quinazolinones modified at N3. All isoxazolidine cycloadducts were screened for antiviral activity against a b...
Autores principales: | Grabkowska-Drużyc, Magdalena, Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Piotrowska, Dorota G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222691/ https://www.ncbi.nlm.nih.gov/pubmed/30060562 http://dx.doi.org/10.3390/molecules23081889 |
Ejemplares similares
-
New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity
por: Piotrowska, Dorota G., et al.
Publicado: (2016) -
Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures
por: Piotrowska, Dorota G., et al.
Publicado: (2017) -
Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones
por: Łysakowska, Magdalena, et al.
Publicado: (2022) -
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues
por: Kokosza, Kamil, et al.
Publicado: (2015) -
Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides
por: Piotrowska, Dorota G., et al.
Publicado: (2019)