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Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway

Acetaminophen (APAP) is a well-known antipyretic and analgesic drug. However, the accidental or intentional APAP overdose will induce liver injury and even acute liver failure. Astragaloside IV (AS-IV), a bioactive compound isolated from Astragali Radix, has been reported to have protective effects...

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Detalles Bibliográficos
Autores principales: Li, Lei, Huang, Wenxiang, Wang, Shoukai, Sun, Kecheng, Zhang, Wenxue, Ding, Yanmei, Zhang, Le, Tumen, Bayaer, Ji, Lili, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222748/
https://www.ncbi.nlm.nih.gov/pubmed/30110942
http://dx.doi.org/10.3390/molecules23082032