Cargando…

Enzyme-Site Blocking Combined with Optimization of Molecular Docking for Efficient Discovery of Potential Tyrosinase Specific Inhibitors from Puerariae lobatae Radix

Enzyme inhibitors from natural products are becoming an attractive target for drug discovery and development; however, separating enzyme inhibitors from natural-product extracts is highly complex. In this study, we developed a strategy based on tyrosinase-site blocking ultrafiltration integrated wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Haichun, Zhu, Yitian, Wang, Ting, Qi, Jin, Liu, Xuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222779/
https://www.ncbi.nlm.nih.gov/pubmed/30314397
http://dx.doi.org/10.3390/molecules23102612