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Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers

Alzheimer’s disease is one of the most common chronic neurodegenerative disorders. Despite several in vivo and clinical studies, the cause of the disease is poorly understood. Currently, amyloid β (Aβ) peptide and its tendency to assemble into soluble oligomers are known as a main pathogenic event l...

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Detalles Bibliográficos
Autores principales: Bartus, Éva, Olajos, Gábor, Schuster, Ildikó, Bozsó, Zsolt, Deli, Mária A., Veszelka, Szilvia, Walter, Fruzsina R., Datki, Zsolt, Szakonyi, Zsolt, Martinek, Tamás A., Fülöp, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222781/
https://www.ncbi.nlm.nih.gov/pubmed/30279351
http://dx.doi.org/10.3390/molecules23102523