CF(3)-Substituted Mollugin 2-(4-Morpholinyl)-ethyl ester as a Potential Anti-inflammatory Agent with Improved Aqueous Solubility and Metabolic Stability

Although mollugin, the main ingredient of the oriental medicinal herb Rubia cordifolia, has considerable anti-inflammatory effects, it has poor aqueous solubility as well as poor metabolic and plasma stability. To overcome these shortfalls, various mollugin derivatives have been synthesized and eval...

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Detalles Bibliográficos
Autores principales: Hong, Ki Bum, Kim, Darong, Kim, Bo-Kyung, Woo, Seo Yeon, Lee, Ji Hoon, Han, Seung-Hee, Bae, Gyu-Un, Kang, Soosung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222789/
https://www.ncbi.nlm.nih.gov/pubmed/30110934
http://dx.doi.org/10.3390/molecules23082030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222789/
https://www.ncbi.nlm.nih.gov/pubmed/30110934
http://dx.doi.org/10.3390/molecules23082030

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