Synthesis of New Triarylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE(2) and Nitric Oxide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages

This article describes the design, synthesis, and in vitro anti-inflammatory screening of new triarylpyrazole derivatives. A total of 34 new compounds were synthesized containing a terminal arylsulfonamide moiety and a different linker between the sulfonamide and pyridine ring at position 4 of the p...

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Detalles Bibliográficos
Autores principales: Abdel-Maksoud, Mohammed S., El-Gamal, Mohammed I., Gamal El-Din, Mahmoud M., Choi, Yunji, Choi, Jungseung, Shin, Ji-Sun, Kang, Shin-Young, Yoo, Kyung Ho, Lee, Kyung-Tae, Baek, Daejin, Oh, Chang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222820/
https://www.ncbi.nlm.nih.gov/pubmed/30301280
http://dx.doi.org/10.3390/molecules23102556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222820/
https://www.ncbi.nlm.nih.gov/pubmed/30301280
http://dx.doi.org/10.3390/molecules23102556

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