Synthesis, Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors

Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In some cancer types the level of COX-2 enzyme is increased indicating that this...

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Detalles Bibliográficos
Autores principales: Coşkun, Göknil Pelin, Djikic, Teodora, Hayal, Taha Bartu, Türkel, Nezaket, Yelekçi, Kemal, Şahin, Fikrettin, Küçükgüzel, Ş. Güniz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222829/
https://www.ncbi.nlm.nih.gov/pubmed/30082676
http://dx.doi.org/10.3390/molecules23081969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222829/
https://www.ncbi.nlm.nih.gov/pubmed/30082676
http://dx.doi.org/10.3390/molecules23081969

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