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An Anti-Inflammatory Azaphenothiazine Inhibits Interferon β Expression and CXCL10 Production in KERTr Cells

An azaphenothiazine derivative, 6-chloroethylureidoethyldiquino[3,2-b;2′,3′-e][1,4]thiazine (DQT), has recently been shown to exhibit immunosuppressive activities in mouse models. It also inhibited the expression of CXCL10 at the protein level, at non-toxic concentrations, in the culture of KERTr ce...

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Detalles Bibliográficos
Autores principales: Strzadala, Leon, Fiedorowicz, Anna, Wysokinska, Edyta, Ziolo, Ewa, Grudzień, Małgorzata, Jelen, Malgorzata, Pluta, Krystian, Morak-Mlodawska, Beata, Zimecki, Michal, Kalas, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222831/
https://www.ncbi.nlm.nih.gov/pubmed/30250011
http://dx.doi.org/10.3390/molecules23102443