Targeting of FGF-Signaling Re-Sensitizes Gastrointestinal Stromal Tumors (GIST) to Imatinib In Vitro and In Vivo

Dysregulation of the fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) signaling pathway is frequently observed in multiple human malignancies, and thus, therapeutic strategies targeting FGFs and FGFRs in human cancer are being extensively explored. We observed the activation o...

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Detalles Bibliográficos
Autores principales: Boichuk, Sergei, Galembikova, Aigul, Dunaev, Pavel, Micheeva, Ekaterina, Valeeva, Elena, Novikova, Maria, Khromova, Natalya, Kopnin, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222839/
https://www.ncbi.nlm.nih.gov/pubmed/30326595
http://dx.doi.org/10.3390/molecules23102643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222839/
https://www.ncbi.nlm.nih.gov/pubmed/30326595
http://dx.doi.org/10.3390/molecules23102643

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