Spatial Overlap of Claudin- and Phosphatidylinositol Phosphate-Binding Sites on the First PDZ Domain of Zonula Occludens 1 Studied by NMR

Background: The tight junction is an intercellular adhesion complex composed of claudins (CLDs), occludin, and the scaffolding proteins zonula occludens 1 (ZO-1) and its two paralogs ZO-2 and ZO-3. ZO-1 is a multifunctional protein that contains three PSD95/Discs large/ZO-1(PDZ) domains. A key funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Hiroaki, Hidekazu, Satomura, Kaori, Goda, Natsuko, Nakakura, Yukako, Hiranuma, Minami, Tenno, Takeshi, Hamada, Daizo, Ikegami, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222848/
https://www.ncbi.nlm.nih.gov/pubmed/30261614
http://dx.doi.org/10.3390/molecules23102465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222848/
https://www.ncbi.nlm.nih.gov/pubmed/30261614
http://dx.doi.org/10.3390/molecules23102465

Ejemplares similares