Discovery of CNS-Like D3R-Selective Antagonists Using 3D Pharmacophore Guided Virtual Screening

The dopamine D3 receptor is an important CNS target for the treatment of a variety of neurological diseases. Selective dopamine D3 receptor antagonists modulate the improvement of psychostimulant addiction and relapse. In this study, five and six featured pharmacophore models of D3R antagonists were...

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Detalles Bibliográficos
Autores principales: Lee, June Hyeong, Cho, Sung Jin, Kim, Mi-hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222863/
https://www.ncbi.nlm.nih.gov/pubmed/30257450
http://dx.doi.org/10.3390/molecules23102452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222863/
https://www.ncbi.nlm.nih.gov/pubmed/30257450
http://dx.doi.org/10.3390/molecules23102452

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