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Suppression of Hepatitis C Virus Genome Replication and Particle Production by a Novel Diacylglycerol Acyltransferases Inhibitor

Diacylglycerol acyltransferases (DGATs) play a critical role in the biosynthesis of endogenous triglycerides (TGs) and formation of lipid droplets (LDs) in the liver. In particular, one member of DGATs, DGAT-1 was reported to be an essential host factor for the efficient production of hepatitis C vi...

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Detalles Bibliográficos
Autores principales: Kim, Dahee, Goo, Ja-Il, Kim, Mi Il, Lee, Sung-Jin, Choi, Moonju, Than, Thoa Thi, Nguyen, Phuong Hong, Windisch, Marc P., Lee, Kyeong, Choi, Yongseok, Lee, Choongho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222871/
https://www.ncbi.nlm.nih.gov/pubmed/30127285
http://dx.doi.org/10.3390/molecules23082083