Discovery of 4,5-Dihydro-1H-thieno[2′,3′:2,3]thiepino [4,5-c]pyrazole-3-carboxamide Derivatives as the Potential Epidermal Growth Factor Receptors for Tyrosine Kinase Inhibitors

The epidermal growth factor receptors (EGFRs), in which overexpression (known as upregulation) or overactivity have been associated with a number of cancers, has become an attractive molecular target for the treatment of selective cancers. We report here the design and synthesis of a novel series of...

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Detalles Bibliográficos
Autores principales: Ke, Jia, Lu, Qi, Wang, Xin, Sun, Rui, Jin, Zhe, Zhan, Xiaoyi, Hu, Jianshu, Wan, David Chi-cheong, Hu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222878/
https://www.ncbi.nlm.nih.gov/pubmed/30096806
http://dx.doi.org/10.3390/molecules23081980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222878/
https://www.ncbi.nlm.nih.gov/pubmed/30096806
http://dx.doi.org/10.3390/molecules23081980

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