Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

The CCAAT enhancer-binding protein α (C/EBPα) plays an important role in myeloid cell differentiation and in the enhancement of C/EBPα expression/activity, which can lead to granulocytic differentiation in acute myeloid leukemia (AML) cells. We found that styryl quinazolinones induce upregulation of...

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Detalles Bibliográficos
Autores principales: Sridhar, Radhakrishnan, Takei, Hisashi, Syed, Riyaz, Kobayashi, Ikei S., Hui, Liu Bee, Kamal, Ahmed, Tenen, Daniel G., Kobayashi, Susumu S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222906/
https://www.ncbi.nlm.nih.gov/pubmed/30081475
http://dx.doi.org/10.3390/molecules23081938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222906/
https://www.ncbi.nlm.nih.gov/pubmed/30081475
http://dx.doi.org/10.3390/molecules23081938

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