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Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα
The CCAAT enhancer-binding protein α (C/EBPα) plays an important role in myeloid cell differentiation and in the enhancement of C/EBPα expression/activity, which can lead to granulocytic differentiation in acute myeloid leukemia (AML) cells. We found that styryl quinazolinones induce upregulation of...
Autores principales: | Sridhar, Radhakrishnan, Takei, Hisashi, Syed, Riyaz, Kobayashi, Ikei S., Hui, Liu Bee, Kamal, Ahmed, Tenen, Daniel G., Kobayashi, Susumu S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222906/ https://www.ncbi.nlm.nih.gov/pubmed/30081475 http://dx.doi.org/10.3390/molecules23081938 |
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