Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes

Chemical probes are of central relevance for chemical biology. To unambiguously explore the role of target proteins in triggering or mediating biological functions, small molecules used as probes should ideally be target-specific; at least, they should have sufficiently high selectivity for a primar...

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Detalles Bibliográficos
Autores principales: Miljković, Filip, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222907/
https://www.ncbi.nlm.nih.gov/pubmed/30249057
http://dx.doi.org/10.3390/molecules23102434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222907/
https://www.ncbi.nlm.nih.gov/pubmed/30249057
http://dx.doi.org/10.3390/molecules23102434

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