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Data-Driven Exploration of Selectivity and Off-Target Activities of Designated Chemical Probes
Chemical probes are of central relevance for chemical biology. To unambiguously explore the role of target proteins in triggering or mediating biological functions, small molecules used as probes should ideally be target-specific; at least, they should have sufficiently high selectivity for a primar...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222907/ https://www.ncbi.nlm.nih.gov/pubmed/30249057 http://dx.doi.org/10.3390/molecules23102434 |