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Liraglutide Treatment Reduces Endothelial Endoplasmic Reticulum Stress and Insulin Resistance in Patients With Diabetes Mellitus

BACKGROUND: Prior studies have shown that nutrient excess induces endoplasmic reticulum (ER) stress in nonvascular tissues from patients with diabetes mellitus (DM). ER stress and the subsequent unfolded protein response may be protective, but sustained activation may drive vascular injury. Whether...

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Detalles Bibliográficos
Autores principales: Bretón‐Romero, Rosa, Weisbrod, Robert M., Feng, Bihua, Holbrook, Monika, Ko, Darae, Stathos, Mary M., Zhang, Ji‐Yao, Fetterman, Jessica L., Hamburg, Naomi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222937/
https://www.ncbi.nlm.nih.gov/pubmed/30371206
http://dx.doi.org/10.1161/JAHA.118.009379