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Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA4‐Dependent CCN1 Secretion

BACKGROUND: Stress‐induced cell premature senescence participates in a variety of tissue and organ remodeling by secreting such proteins as proinflammatory cytokines, chemokines, and growth factors. However, the role of cardiomyocyte senescence in heart remodeling after acute myocardial infarction h...

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Detalles Bibliográficos
Autores principales: Cui, Sumei, Xue, Li, Yang, Feihong, Dai, Shuai, Han, Ziqi, Liu, Kai, Liu, Baoshan, Yuan, Qiuhuan, Cui, Zhaoqiang, Zhang, Yun, Xu, Feng, Chen, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222958/
https://www.ncbi.nlm.nih.gov/pubmed/30371213
http://dx.doi.org/10.1161/JAHA.118.009111