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Primary Effect of SERCA2a Gene Transfer on Conduction Reserve in Chronic Myocardial Infarction

BACKGROUND: SERCA2a gene transfer (GT) improves mechano‐electrical function in animal models of nonischemic heart failure Whether SERCA2a GT reverses pre‐established remodeling at an advanced stage of ischemic heart failure is unclear. We sought to uncover the electrophysiological effects of adeno‐a...

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Detalles Bibliográficos
Autores principales: Motloch, Lukas J., Cacheux, Marine, Ishikawa, Kiyotake, Xie, Chaoqin, Hu, Jun, Aguero, Jaume, Fish, Kenneth M., Hajjar, Roger J., Akar, Fadi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222964/
https://www.ncbi.nlm.nih.gov/pubmed/30371209
http://dx.doi.org/10.1161/JAHA.118.009598