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Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris
BACKGROUND: Proprotein convertase furin is responsible for the processing of a wide variety of precursors consisted of signal peptide, propeptide and mature peptide in mammal. Many precursors processed by furin have important physiological functions and can be recombinantly expressed in Pichia pasto...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223083/ https://www.ncbi.nlm.nih.gov/pubmed/30409181 http://dx.doi.org/10.1186/s12934-018-1020-x |